I took Paxil some years ago for depression, and when I stopped, the withdrawal symptoms were horrific. I suffered “brain zaps.” It was the worst thing I’ve ever been through.
The commercial says it’s the only nonhormonal option. Is that really true?
The ad doesn’t mention that the active ingredient in Brisdelle, paroxetine, was originally used as an antidepressant. Nor does it say that stopping paroxetine suddenly can be hard.
Most importantly, the commercial does not tell how well it works. The difference between Brisdelle and placebo was two fewer hot flashes per day. While that is statistically significant, it is hardly impressive, especially since women had to experience at least seven flushes a day to be included in the study.
Side effects of Brisdelle include headache, nausea, vomiting and fatigue. Suicidal thoughts also may occur on occasion. There may be a side effect on the wallet too. One woman said her Brisdelle bill was $178 for a month’s supply. A low dose of generic paroxetine, though not approved for hot flashes, runs about $4.
Vitamin D and psoriasis
A surprising number of people have inadequate levels of vitamin D, especially during the winter.
I was pleased with the savings, but my pain has grown worse daily. Have other people found that generic celecoxib is not as effective as Celebrex?
Reach Joe and Terry Graedon at PeoplesPharmacy.com.