The ramp from Interstate 40 East to Interstate 77 North in Statesville is blocked Friday morning by an overturned 18-wheeler.
It could take until noon to remove the truck, according to the state Department of Transportation.
In other traffic news, East Seventh Street between North College and North Brevard streets will close at 7 a.m. Saturday until 12:01 a.m. Monday to accommodate construction for the Lynx Blue Line Extension.
Drivers can use the detour route of North College to East Eighth to North Brevard to East Sixth.
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Access to homes will be maintained. CATS service will be unaffected.