NORTH CAROLINA (1-7, 1-5 ACC) at DUKE (6-3, 2-3)
Wallace Wade Stadium, Durham, 12:20 p.m., WBTV
Duke showed a ground game last week against Miami, with Deon Jackson rushing for 113 yards. Tar Heels quarterback Nathan Elliott (three interceptions last week) will need a big day to keep up with QB Daniel Jones and the Blue Devils’ offense.
No. 2 CLEMSON (9-0, 6-0 ACC) at No. 17 BOSTON COLLEGE (7-2, 4-1)
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Alumni Stadium, Chestnut Hill, Mass., 8 p.m., WSOC
The Eagles likely will try to control the tempo behind running back A.J. Dillon (nearly 900 rushing yards), and they have a sound defense. But Clemson has been ferocious in recent weeks behind QB Trevor Lawrence (18 touchdown passes to just three interceptions). ESPN’s Game Day will be in Chestnut Hill.
SOUTH CAROLINA (5-3, 4-3 SEC) at No. 19 FLORIDA (6-3, 4-3)
Ben Hill Griffin Stadium, Gainesville, Fla., noon, ESPN
Florida’s offense is struggling, but the Gamecocks’ injury-riddled defense gave up 600 yards to Mississippi last week. The Gators’ tough defense was shredded last week by Missouri, so the key might be if Gamecocks QB Jake Bentley and the offense can move the ball.
EAST CAROLINA (2-6, 0-5 American Athletic) at TULANE (4-5, 3-2)
Yulman Stadium, New Orleans, 4 p.m., ESPN News
Tulane is coming off a big upset of South Florida and features both a strong running game (led by RB Corey Dauphine) and an aggressive defense that leads the league in sacks. Freshman Holton Ahlers, the likely QB starter for the Pirates, has looked sharp in recent appearances.
CHARLOTTE (4-5, 3-2 Conference USA) at MARSHALL (5-3, 3-2)
Joan C. Edwards Stadium, Huntington, W.Va., 2:30 p.m.
Statistics indicate neither team will run the ball well, as the 49ers rank No. 1 in the conference in rushing defense, and Marshall is second. The 49ers are likely to pressure Marshall QB Alex Thompson, who has started the past four games, throwing five touchdowns against three interceptions.
APPALACHIAN STATE (6-2, 4-1 Sun Belt) at TEXAS STATE (3-6, 1-4)
Bobcat Stadium, San Marcos, Texas, 4 p.m.
Texas State, coming off an upset victory over Georgia Southern, is coached by former West Charlotte High and Appalachian State standout Everett Withers. ...App State linebacker Jacob Fehr (Providence High) is Sun Belt Defensive Player of the Week after a three-sack, eight-tackle performance last week against Coastal Carolina.
ARKANSAS STATE (5-4, 2-3 Sun Belt) at COASTAL CAROLINA (5-4, 2-3)
Brooks Stadium, Conway, S.C., 5 p.m.
This is a bowl-eligibility game for the winner. The Chanticleers must slow down Arkansas State QB Justice Hansen, who is averages nearly 280 passing yards a game. The Red Wolves lead the conference in overall offense.
GARDNER-WEBB (3-6, 2-1 Big South) at CHARLESTON SOUTHERN (3-5, 1-2)
Buccaneer Field, Charleston, S.C., 3 p.m.
The visiting Runnin’ Bulldogs are aiming for their first three-game conference winning streak in 15 years. QB Jordan Smith has seven touchdown passes in the past two games. But the Buccaneers are second in Football Championship Subdivision in pass defense, allowing an average of 134.5 yards a game.
DAVIDSON (5-4, 2-4 Pioneer Football) at SAN DIEGO (7-2, 6-0)
Torero Stadium, San Diego, 5 p.m.
Six Wildcats have rushed for 100 or more yards in a game this season. ...San Diego has not lost a home conference game since 2010 and has a 27-game conference winning streak. QB Anthony Lawrence has accounted for more than 3,000 yards offense this season.